 Jintropin ® 10iu
Substance: Human Growth Hormone
Delivery:
20vials/10IU
Manufacturer: China, GenSci
All kit boxes are sealed from the factory with a tamper-proof sticker which can be verified for authenticity on www.315net.com
As with no other doping drug, growth hormones are still surrounded
by an aura of mystery. Some call it a wonder drug which causes gigantic
strength and muscle gains in the shortest time. Others consider it completely
useless in improving sports performance and argue that it only promotes
the growth process in children with an early stunting of growth. Some
are of the opinion that growth hormones in adults cause severe bone
deformities in the form of overgrowth of the lowerjaw and extremities.
And, generally speaking, which growth hormones should one take the human
form, the synthetically manufactured version, recombined or genetically
produced form and in which dosage?
All this controversy about growth
hormones is so complex that the reader must have some basic information
in order to understand them. The growth hormones is a polypeptide hormone
consisting of 191 amino acids. In humans it is produced in the hypophysis
and released if there are the right stimuli (e.g. training, sleep, stress,
low blood sugar level). It is now important to understand that the freed
HGH (human growth hormones) itself has no direct effect but only stimulates
the liver to produce and release insulin-like growth factors and somatomedins.
These growth factors are then the ones that cause various effects on
the body. The problem, however, is that the liver is only capable of
producing a limited amount of these substances so that the effect is
limited.
If growth hormones are injected they only stimulate the liver
to produce and release these substances and thus, as already mentioned,
have no direct effect. The use of these STH somatotropic hormone compounds
offers the athlete three performance-enhancing effects.
STH (somatotropic
hormone) has a strong anabolic effect and causes an increased protein
synthesis which manifests itself in a muscular hypertrophy (enlargement
of muscle cells) and in a muscular hyperplasia (increase of muscle cells.)
The latter is very interesting since this increase cannot be obtained
by the intake of steroids. This is probably also the reason why STH
is called the strongest anabolic hormone. The second effect of STH is
its pronounced influence on the burning of fat. It turns more body fat
into energy leading to a drastic reduction in fat or allowing the athlete
to increase his caloric intake. Third, and often overlooked, is the
fact that STH strengthens the connective tissue, tendons, and cartilages
which could be one of the main reasons for the significant increase
in strength experienced by many athletes. Several bodybuilders and powerlifters
report that through the simultaneous intake with steroids STH protects
the athlete from injuries while inereasing his strength.
You will say that this sounds just wonderful. What is the problem, however
since there are still some who argue that STH offers nothing to athletes?
There are, by all means, several athletes who have tried STH and who
were sadly disappointed by its results. However, as with many things
in life, there is a logical explanation or perhaps even more than one:
1. The athlete simply has not taken a sufficient amount of STH regularly
and over a long enough period of time. STH is a very expensive compound
and an effective dosage is unaffordable by most people.
2. When using STH the body also needs more thyroid hormones,insulin,
corticosteroids, gonadotropins, estrogens and what a surprise androgens
and anabolics. This is also the reason why STH, when taken alone, is
considerably less effective and can only reach its optimum effect by
the additive intake of steroids, thyorid hormones, and insulin, in particular.
But we must point out in this case that STH has a predominantly anabolic
effect. There are three hormones which are needed at the same time in
order to allow for maximum anabolic effect. These are STH, insulin,
and an LT-3 thyroid hormone, such as, for example, Cytomel. Only then
can the liver produce and release an optimal amount of somatomedin and
insulin-like growth factors. This anabolic effect can be further enhanced
by taking a substance with an anticatabolic effect. These substances
are-everybody should probably know by now-anabolic/androgenic steroids
or Clenbuterol. Then a synergetic effect takes place.'Are you still
wondering why pro bodybuilders are so incredibly massive but, at the
same time, totally ripped while you are not. Most athletes have tried
STH during preparation for a competition in that phase when the diet
is calorie-reduced. The body usually reacts by reducing the release
of insulin and of the L-T3 thyroid hormone. And, as was described under
point 2, this is not an advantageous condition when STH is expected
to work well. Well, we almost forgot. Those who combine Clenbuterol
with STH, should know that Clenbuterol (like Ephedrine) reduces the
body's own release of insulin and L-T3. True, this seems a little complicated
and when reading it for the first time it might be a little confusing;
however it really is true: STH has a significant influence on several
hormones in the human body; this does not allow for a simple administration
schedule. As said, STH is not cheap and those who intend to use it should
know a little more about it. If you only want to burn fat with STH you
will only have to remember user information for the part with the L-T3
thyroid hormone as is printed by Kabi Pharmacia GmbH for their compound
Genotropin: "The need of the thyroid hormone often inereases during
treatment with growth hormones."
3. Since most athletes who want to use STH can only obtain it if prescribed
by a physician, the only supply source remains the black market. And
this is certainly another reason why some athletes might not have been
very happy with the effect of the purchased compound. How could he,
if cheap HCG was passed off as expensive STH? Since both compounds are
available as dry substances, all that would be needed is a new label
of Serono's Saizen or Lilly's Humatrope on the HCG ampule. It is no
longer fun when somebody is paying $200 for 5000 I.U. of HCG, only worth
$ 30, and thinking that he just purchased 4 I.U. of HGH. And if you
think this happens only to novices and to the ignorant, ask Ben Johnson.
"Big Ben," who during three tests within five days showed
an above-limit testosterone level, was not a victim of his own stupidity
but more likely the victim of fraud. According to statistics by the
German Drug Administration, 42% of the HGH vials confiscated on the
North American black market are fakes. In addition to a display of labels
in the Dutch or Russian language the fakes are distinguished from the
original product, in sofar as the dry substance is not present as lyophilic
but present as loose powder. The fakes confiscated so far use the name
"Humatrope 16" under the name of Lilly Company (with Dutch
denomination) or "Somatogen" (in Russian)." Nowhere can
this much money be made except by faking STH. Who has ever held original
growth hormones in his hand and known how they should look?
4. In a few very rare cases the body reacts by developing antibodies
to the exogenous STH, thus making it ineffective.
The question of the right dosage, as well as the type and duration of
application, is very difficult to answer. Since there is no scientificresearch
showing how STH should be taken for performance improvement, we can
only rely on empirical data, that is experimental values. The respective
manufacturers indicate that in cases of hypophysially stunted growth
due to lacking or insuffieient release of growt hormones by the hypophysis,
a weekly average dose of 0.3 I.U/ week per pound of body weight should
be taken. An athlete weighting 200 pounds, therefore, would have to
inject 60 I.U. weekly. The dosage would be divided into three intramuscular
injections of 20 I.U. each. Subcutaneous injections (under the skin)
are another form of intake which, however would have to be injected
daily, usually 8 I.U. per day. Top athletes usually inject 8-20 I.U./day.
Ordinarily, daily subcutaneous injections are preferred. Since STH has
a half life time of less than one hour, it is not surprising that some
athletes divide their dail dose into three or four subcutaneous injections
of 2-4 I.U. each. Application of regular small dosages seems to bring
the most effective results. This also has its reasons: When STH is injected,
serum concentration in the blood rises quickly, meaning that the effect
is almost immediate. As we know, STH stimulates the liver to produce
and release somatomedins and insulin like growth factors which in turn
effect the desired results in the body. Since the liver can only produce
a limited amount of these substances, we doubt that larger STH injections
will induce the liver to produce instantaneously a larger quantity of
somatomedins and insulin-like growth factors. It seems more likely that
the liver will react more favorably to smaller dosages. If the STH solution
is injected subcutaneously several consecutive times at the same point
of injection, a loss of fat tissue is possible. Therefore, the point
of injection, or even better, the entire sisde of the body should be
continuously, changed in order to avoid a loss of local fat tissue (lipoathrophy)
in the injection cell. One thing has manifested itself over the years:
The effect of STH is dosage-dependent. This means either invest a lot
of money and do it right or do not even begin. Half-hearted attempts
are condemned to failure Minimum effective dosages seem to start at
4 I.U. per day. For comparison: the hypophysis of a healthy; adult,
releases 0.5-1.5 I.U. growth hormones daily. The duration of intake
usually depends on the athlete's financial resources. Our experience
is that STH is taken over a prolonged period, from at least six weeks
to several (3-4)months. It is interesting to note that the effect of STH
does not stop after a few weeks; this usually allows for continued improvements
at a steady dosage. Bodybuilders who have had positive results with
STH have reported that the build-up strength and, in particular, the
newly-gained muscle system were essentially maintained after discontinuance
of the product. It remains to be clarified what happens with the insulin
and LT-3 thyroid hormone. Athletes who take STH in their build-up phase
usually do not need exogenous insulin. It is recommended, in this case,
that the athlete eats a complete meal every three hours, resulting in
6-7 meals day. This causes the body to continuously release insulin
so that the blood sugar level does not fall too low. The use of LT-3
thyroid hormones, in this phase, is carried out reluctantly by athletes.
In any case, you must have a physician check the thyroid hormone level
during the intake of STH. Simultaneous use of anabolic /androgenic steroids
and/or Clenbuterol is usually appropriate. During the preparation for
a competition the use of thyroid hormones steadily inereases. Sometimes
insulin is taken together with STH, as well as with steroids and Clenbuterol.
Apart from the high damage potential that exogenous insulin can have
in non-diabetics, incorrect use will simply and plainly make you "FAT!
Too much insulin activates certain enzymes which convert glucose into
glycerol and finally into triglyceride. Too little insulin, especially
during a diet, reduces the anabolic effect of STH. The solution to this
dilemma? Visiting a qualified physician who advises the athlete during
this undertaking and who, in the event of exogenous insulin supply,
checks the blood sugar level and urine periodically. According to what
we have heard so far, athletes usually inject intermediately-effective
insulin having a maximum duration of effect of 24 hours once a day.
Human insulin such as Depot-H-Insulin Hoechst is generally used. Briefly-effective
insulin with a maximum duration of effect of eight hours is rarely used
by athletes. Again a human insulin such as H-Insulin Hoechst is preferred.
The undesired effect of growth hormones, the so-called side effects,
are also a very interesting and hotly-discussed issue. Above all it
must be said: STH has none of the typical side effects of anabolic/androgenic
steroids including reduced endogenous testosterone production, acne,
hair loss, aggressiveness, elevated estrogen level, virilization symptoms
in women, and increased water and salt retention. The main side effects
that are possible with STH are an abnormally small concentration of
glucose in the blood (hypoglycemia) and an inadequate thyroid function.
In some cases antibodies against growth hormones are developed but are
clinically irrelevant. What about the horror stories about acromegaly,
bone deformation, heart enlargement, organ conditions, gigantism, and
early death? In order to answer this question a clear differentiation
must be made between humans before and after puberty. The growth plates
in a person continue to grow in length until puberty. After puberty
neither an endogenous hypersection of growth hormones nor an excessive
exogenous supply of STH can cause additional growth in the length of
the bones. Abnormal size (gigantism) initially goes hand in hand with
remarkable body strength and muscular hardness in the afflicted; later,
if left untreated, it ends in weakness and death. Again, this is only
possible in pre-pubescent humans who also suffer from an inadequate
gonadal function (hypogonadism). Humans who suffer from an endogenous
hypersecrehon after puberty and whose normal growth is completed can
also suffer from acromegaly. Bones become wider but not longer. There
is a progressive growth in the hands and feet and enlargement of features
due to the growth of the lower jaw and nose. What the authorities like
to do now is to present extreme cases of athletes suffering from these
malfunctions in order to discourage others and to drum into athletes
the fact that with the exogenous supply of growth hormones they would
suffer the same destiny. This, however, is very unlikely, as reality
has proven. Among the numerous athletes using STH comparatively few
are seven feet tall Neanderthalers with a protruded lower jaw, deformed
skull, claw like hands, thick lips, and prominent bone plates who walk
around in size 25 shoes. In order to avoid any misunderstandings, we
do not want to disguise the possible risks of exogenous STH use in adults
and healthy humans, but one should at least try to be openminded. Acromegaly,
diabpetes, thyroid insuficiency, heart muscle hypertrophy, high blood
ressure, and enlargement of the kidneys are theoretically possible if
STH is used excessively over prolonged periods of time; however, in
reality and particularly when it comes to the external attributes, these
are rarely present. Some athletes report headaches, nausea, vomiting,
and visual disturbances during the first weeks of intake. These symptoms
disappear in most cases even with continued intake. The most common
problems with STH occur when the athlete intends to inject insulin in
addition to STH. The substance somatropin is available as a dried powder
and before injecting it must be mixed with the enclosed solution-containing
ampule. The ready solution must be injected immediately or stored in
the refrigerator for up to 24 hours. It is usually recommended that
the compound be stored in the refrigerator. With the exception of the
remedy Saizen the biological activity of growth hormones is usually
not impaired when storing the dry substance at 15-25 C (room temperature);
however, a cooler place (2-8° C) is preferable. It is noted that
for the U.S.-American growth hormones compounds, the substance content
is not given in I.U.(International Units) but in mg (milligrams). Since
l mg corresponds to exactly 2.7 I.U. the 5mg solution of the compound
Humatrope by Lilly contains exactl 13.5 I.U. of Somatropin. The 10 mg
solution of the Protropin compound by the Genentech therefore contains
27 I.U. of Somatropin. In American powerlifting and bodybuilding circles
Humatrope is usually preferred over Protropin. The reason is that Humatrope
is synthesized from a chain of 191 amino acids and thus is identical
to the amino acid sequence of the human growth hormones. Protropin,
on the other hand, consists of 192 amino acids, one amino acid too many.
This might be the explanation for why more antibodies are developed
with Protropin than with Humatrope. Growth hormones are on the doping
list but they are not yet detectable during doping tests.
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